William Turpen married Louise Anne (Anna) Turpin who was Newt Turpin's daughter and William's cousin.
They had five children:
James N. (b. 1870 IA), Mary (b. 1873 IA), Susan E. (b. @1875 IA), Katherine “Kate” (b. @ 1877 IA), and Carrie B. (b. 1880 IA).
Anna died in 1880, perhaps in childbirth. This left Will with the difficult task of raising small children. He remarried 9 August 1887 to Mary A. Edwards. Anna is buried in the Pleasant Hill Cemetery in Greene County, Iowa. Will died in 1923.